Determining what is in a sample, and how much.
10 topics · 10 curated works
No prior grounding assumed.
Analytical Chemistry 2.1
David T. Harvey · 2016
A free, complete analytical chemistry course covering sampling, calibration and the major instrumental and wet-chemical methods, built as an open…
Assumes you know the vocabulary.
The Development of Partition Chromatography
A. J. P. Martin & R. L. M. Synge · 1952
Introduces partition chromatography, separating mixtures by the differing solubility of each component between two immiscible liquid phases rather…
+2 more at this level
Primary sources and full treatments.
The Scientific Foundations of Analytical Chemistry
Wilhelm Ostwald · 1894
Argues that titrimetric and gravimetric procedures are applied chemical equilibrium, not a separate craft, so their accuracy and limits follow from…
+5 more at this level
10 works
David T. Harvey
A free, complete analytical chemistry course covering sampling, calibration and the major instrumental and wet-chemical methods, built as an open alternative to a commercial textbook.
link checked 17 Sept 2026A. J. P. Martin & R. L. M. Synge
Introduces partition chromatography, separating mixtures by the differing solubility of each component between two immiscible liquid phases rather than by adsorption.
link checked 17 Sept 2026John B. Fenn
Explains how spraying a solution through a charged needle gets large, fragile biomolecules into the gas phase intact, making mass spectrometry applicable to whole proteins.
link checked 17 Sept 2026National Research Council
Finds that, apart from nuclear DNA analysis, no forensic method had been rigorously shown to reliably connect evidence to a specific source, and recommends removing crime laboratories from police control.
link checked 17 Sept 2026Wilhelm Ostwald
Argues that titrimetric and gravimetric procedures are applied chemical equilibrium, not a separate craft, so their accuracy and limits follow from the same mass-action law that governs any reaction in solution.
link checked 17 Sept 2026C. V. Raman
Reports that a small fraction of scattered light shifts frequency by an amount set by the scattering molecule's own vibrations, giving a new spectroscopic probe of molecular structure.
link checked 17 Sept 2026Jaroslav Heyrovský
Introduces the dropping-mercury electrode to record current-voltage curves that identify and quantify dissolved species from a single measurement.
link checked 17 Sept 2026Dorothy Crowfoot Hodgkin
Describes how X-ray diffraction determined the full three-dimensional structures of penicillin, vitamin B12 and insulin, molecules too complex for earlier crystallographic methods.
link checked 17 Sept 2026Richard R. Ernst
Replaces the slow point-by-point frequency sweep of early NMR with a single pulse and a Fourier transform, cutting acquisition time enough to make multidimensional NMR practical.
link checked 17 Sept 2026Svante Wold
Defines chemometrics as extracting chemical information from measured data by statistical and mathematical methods, distinguishing it from simply running software on lab results.