Project Sherlock

Neuroscience

Systems Neuroscience

Circuits that compute something identifiable.

10 topics · 16 curated works

Topics

Reading in Systems Neuroscience

16

A way in

  1. Start here

    No prior grounding assumed.

    Eye, Brain, and Vision

    David H. Hubel · 1988

    Walks a general reader through how the visual system builds edges, motion and depth from raw retinal input, using the author's own Nobel-winning…

  2. Then

    Assumes you know the vocabulary.

    The Neural Origin of Muscle Synergies

    Bizzi & Cheung · 2013

    Argues the nervous system controls complex movement by combining a small number of fixed muscle synergies rather than specifying every muscle…

    +1 more at this level

  3. Go deeper

    Primary sources and full treatments.

    Somatic Motor and Sensory Representation in the Cerebral Cortex of Man as Studied by Electrical Stimulation

    Penfield & Boldrey · 1937

    Maps the body's sensory and motor representation across the human cortex from direct electrical stimulation during surgery, producing the…

    +12 more at this level

12 of 16 works

Book1988

Eye, Brain, and Vision

David H. Hubel

Walks a general reader through how the visual system builds edges, motion and depth from raw retinal input, using the author's own Nobel-winning experiments as the throughline.

Talk2019

How Your Brain Maps The World

John O'Keefe (The Royal Institution)

Sets out the discovery that hippocampal place cells fire at specific locations and grid cells tile space hexagonally, giving the brain a metric map rather than a list of landmarks.

link checked 17 Sept 2026
Paper1937

Somatic Motor and Sensory Representation in the Cerebral Cortex of Man as Studied by Electrical Stimulation

Penfield & Boldrey

Maps the body's sensory and motor representation across the human cortex from direct electrical stimulation during surgery, producing the somatosensory and motor homunculus.

Paper1957

Modality and Topographic Properties of Single Neurons of Cat's Somatic Sensory Cortex

Vernon B. Mountcastle

Establishes that neurons in somatosensory cortex are organised into vertical columns sharing a single receptive field and modality, the founding evidence for cortical columnar organisation.

Book1960

Experiments in Hearing

Georg von Békésy

Reports the physical mechanics of how the cochlea performs frequency analysis via a travelling wave along the basilar membrane, the experimental basis for modern models of hearing.

Paper1991

A Novel Multigene Family May Encode Odorant Receptors: A Molecular Basis for Odor Recognition

Buck & Axel

Identifies a large family of genes encoding odorant receptors, showing how a limited receptor repertoire could in principle discriminate a vast number of smells.

Paper2005

An Integrative Theory of Locus Coeruleus-Norepinephrine Function: Adaptive Gain and Optimal Performance

Aston-Jones & Cohen

Proposes that the locus coeruleus norepinephrine system switches the brain between exploitative and exploratory behavioural modes by adjusting neural gain.

In order written

1937 – 2019
  1. 1937Somatic Motor and Sensory Representation in the Cerebral Cortex of Man as Studied by Electrical StimulationPenfield & Boldrey
  2. 1957Modality and Topographic Properties of Single Neurons of Cat's Somatic Sensory CortexVernon B. Mountcastle
  3. 1960Experiments in HearingGeorg von Békésy
  4. 1988Eye, Brain, and VisionDavid H. Hubel
  5. 1991A Novel Multigene Family May Encode Odorant Receptors: A Molecular Basis for Odor RecognitionBuck & Axel
  6. 2005An Integrative Theory of Locus Coeruleus-Norepinephrine Function: Adaptive Gain and Optimal PerformanceAston-Jones & Cohen
  7. 2006Efficient auditory codingSmith & Lewicki
  8. 2006The Receptors and Cells for Mammalian TasteChandrashekar, Hoon, Ryba & Zuker
  9. 2006Rhythms of the BrainGyörgy Buzsáki
  10. 2019How Your Brain Maps The WorldJohn O'Keefe (The Royal Institution)

Elsewhere in Neuroscience